Tip #1 A virus usually has a signature, so using a trusted antivirus will help detect and stop it from infecting your systems.
Note: Sometimes viruses have several variants that cannot be detected by an antivirus. This is because of unavailability of a signature or heuristic pattern for a new variant, which is usually addressed in some time.
A virus usually spreads via a:
b) Drive by downloads
d) Rerouting a Web
So, be watchful during these activities.
Tip #2: Disable Autorun on your system and ensure you scan your USB before use. Some antiviruses have options to automate the process.
Tip #3: Use a secure browser and an updated browser. Browser exploits are very common and an updated browser reduces the threat surface by a lot. As an additional security measure, using a No Script Plugin can disable scripts from all websites and you can white list trusted websites to run script.
Tip #4: Do not open email/links that seem suspicious or are not intended for you.
Tip #5: Most antiviruses have browser protection. Just ensure that the feature is enabled.
Tip #6: Use a host firewall and ensure inbound connections are in block mode unless absolutely required.
Tip #7: This is a PRO-TIP ensure all unnecessary services are turned off if not required. Configuring your system to match the CIS Hardening Checklist for Windows is a good approach.